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Aim: We explored the ability of the Hammersmith Infant Neurological Examination HINE to identify typical and delayed cognitive performance in a large population of infants born preterm, both with and without cerebral palsy CP. Method: We conducted a retrospective study of infants born preterm who had repeated HINEs between 3 and 12 months corrected age. The predictive validity of HINE scores for significantly delayed cognitive performance, in children with and without CP, was calculated using specific cut-off scores according to age at assessment.
Results: Of eligible infants gestational age wks, mean [SD] Of the infants who developed CP, the MDI was typical in 28, mildly delayed in 27, and less than 70 in HINE scores showed a good sensitivity and specificity, especially after 3 months, for detecting significantly delayed cognitive performance in infants without CP. In those who developed CP, the score was associated with their cognitive level.
Interpretation: The HINE provides information about the risk of delayed cognitive performance in infants born preterm with and without CP. What this paper adds The Hammersmith Infant Neurological Examination HINE can be used in the first year to identify infants born preterm at risk for delayed cognitive performance. Age-dependent HINE cut-off scores are proposed for detecting increased risk of delayed cognitive performance.
Resultados: De 1. Abstract in English, Spanish, Portuguese.