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Obesity is an excessive fat accumulation due to an imbalance between energy intake and consumption. Central obesity, represented by an increase in Waist Circumference WC and waist-to-hip ratio, is a predictor for obesity-related metabolic disorders and has replaced BMI to determine the clinical diagnosis of metabolic syndrome. Lipid accumulation product calculated from WC and fasting triglyceride concentration is presumed to be an alternative to measure excessive lipid accumulation and a marker to predict diabetes or cardiovascular risk.
Lipid accumulation product is related to cardiovascular disease, diabetes, and metabolic syndrome and is preferable to BMI to identify diseases. It has been established that obesity and increased visceral adipocytes contribute to increased levels of some inflammatory proteins such as CRP. This cross-sectional study involved female with obesity aged years at Diponegoro National Hospital, Semarang, carried out from February to May World Health Organization. Obesity: preventing and managing the global epidemic: Report of a WHO consultation.
Who Technical Report Series Vuori I. World Health Organization and physical activity. Progress in preventive medicine, ; 6. J Am Coll Cardiol, ; 78 22 : e—e Prevalence and related factors of metabolic syndrome in Beijing, China year Obes Facts, ; Lipid accumulation product or lap as an up-to-date clinical biochemical marker of human obesity.
Health Risk Analysis, ; Association and interaction analysis of lipid accumulation product with impaired fasting glucose risk: A cross-sectional survey. Hindawi Journal of Diabetes Research, ; Adult obesity complications: challenges and clinical impact.
Therapeutic Advances in Endocrinology and Metabolism, ; Association of dietary patterns with visceral adiposity, lipid accumulation product, and triglyceride-glucose index in Iranian adults. Clinical Nutrition Research, ; Chawla S, Gitanjali, Bhatti S.